I built a plexiglass encasement for my Ultimaker 2. It includes an upper encasement with openable upper lid, a front openable door, and a rear HEPA filtration unit. The HEPA filtration unit has been designed for compatibility with readily available vacuum cleaner HEPA cartridges. An exhaust fan is mounted to the exterior surface of the rear plexiglass panel. The front door includes hinges, and a pair of door locks that you rotate to lock the front door closed.
Because my Ultimaker 2 is my baby, I designed the enclosure completely non-destructively. None of the components are fastened to the Ultimaker by screws or the like. Instead, the upper encasement is mounted by Mounting Clips that frictionally engage the upper frame of the Ultimaker, and the door is mounted by hinges that frictionally engage the front frame of the Ultimaker. All components are printed in Ultimaker Metallic Grey.