I won't bother burying the lead here, it's all about zip-ties. I've only had my Ultimaker for 3 weeks, but it seems to have solved the only issue I had after my build.
Like others, I have a lot of issues with the horseshoe clip just not putting enough pressure on the clamp. Owen's Hot End mod worked for a while, but I just couldn't keep it tight enough. Part of the problem is that the bowden tube was pretty eaten up from the teeth on the clamp...at one point I even cut a clean edge on the feed side of the tube and flipped it around. This held for around 3 hours of printing before anot