Thanks so much for your help!
I have made the changes suggested, except for the travel speed - when I set it to 150mm/s Cura highlighted it yellow suggesting it was too high. So i made it 140mm/s. But everything else is as you suggest above.
However...it is still not printing well! See photo attached. The PLA doesn't seem to be sticking properly.
Any more suggestions?
Thank you
Alexa