Teacher at a high school here. I teach engineering courses, so my students have a fair bit of experience in the CAD world.
1. For students in my experience, there are few barriers in the use of the tools when they use Cura, the basic profiles get them moving, the largest problem would be with supports or when using unique filaments. Most of the prints my students make end up prototyped in PLA and then if tolerances and fit are appropriate then they move to something more appropriate for the need. Nylon, PETG, etc. I would say our largest challenge is getting them to dive into the material properties more, the technology is readily usable by the kids in my opinion.
2. For the teacher perspective, it depends on the angle, for me it is no major problem as I am in control of all of our printers so I can teach my students how to operate them and maintain them and they can take charge of that with supervision. The biggest challenge is managing time for printing if you only have one or two machines.
3. Admin, I am not admin, but have spoken to many about this, I hear the same things come up. One being how do we get our teachers on the same page of how to use this so its useful for more than just engineering and science teachers, and two the concern with long prints and over night printing.