I've been 2.3b since it was available and it generally works great compared to 2.1, however a few problems I've noticed. (some of which are in 2.1 and 15 as well).
Layer view speed - Much faster most of the time, however with fairly complex models it seems to be both very slow at the 'processing layers' step AND that particular step seems to run on/block the main thread/run loop. For a model I've been working on for a few weeks which originates in openscad it can take upwards of 30s for that layer view step while nothing else I use takes that long to visualize either the stl or the finished gcode. The gcode ends up around 9MB for that and works fine.
Settings saving - Seems to work far better than before but confusingly 'loses' some settings when you save to a _new_ profile. Perhaps because it doesn't save material settings with the profile settings those settings get reset?
Concentric infill - It's really easy to generate a degenerate concentric infill where there's an inverted unsupported cone in the middle of the infill. I would love to be able to use concentric more frequently for transparent/translucent filaments... But I often cannot because of this problem.
Double walls - There still seems to be a problem where sometimes you have to fudge your wall sizes a lot to get cura to actually fill in your walls when not on the top or bottom skins. It seems like in most cases like this, it should be either generating the outer walls and then a single inner wall between them, OR putting a little bit of (100%) infill there. Instead neither thing happens and it just ends up hollow.