I'm using Windows 10 on a I7 4790k and a MSI HD7950 and 8GB of ram, according to the faq that should work just fine. It also runs perfectly on my laptop (Core I3 5010U, Intel HD graphics, 4GB ram) but it just won't boot at my desktop.
I deleted all the user related files in AppData that I could find. But I don't see how any old files could still be there as I did a complete clean install of windows. I have had this everytime on my PC but not on my desktop, so when I'm back at home I'll check the programs running on each and see what might cause a problem.