I'm fairly certain that I found the issue in our case.
As noted, I ran the last print through the PrintDry we have. I got a 30+ hour print complete with one unrelated issue. I couldn't get more than 3 or so before. The setup resulted in very little 'webbing' or whatever people call it. I have less than an 1/8" of that running up the side pointing directly at the material tower printed in the back right corner. That seems fairly normal to me.
The issue i did have is the design of the print dry. When you set the material on the spool holder, it has line a 1/2" or more gap underneath. As the PVA is pulled into the printer, it unspools a bit. That unspooled are can and will go below your spool and get caught in the assembly under the spindle which will lock up your PVA and case the same error - which is this one single instance was because the material could not spool from being jammed. I fixed the jam and put the spool flat on the bottom of the dryer and it completed the last 20 hours or so without issue.
To be clear, prior to using the printdry is when we got this error of a material being out. And it did occur multiple times inside the 3 hour mark, and it would happen repeatedly. I believe the PrintDry fixed that issue. Whether that is a solution for everyone, i can't say. But it does seem to be the answer in our case. And, FWIW, we have these throughout our building in the general office area and not in a controlled room/area.