I'm having the same issue with our S5. It seems to be mostly one specific filament type (blue Matter Hackers PLA). I'm curious what the S5 is actually checking since it mainly seems to be this one filament. I've tested the friction in the Bowden tube, drag of the spool itself, cleaned the extruder, changed the extruder. This filament is also having trouble "sticking" so I suspect the problem may be related. During the print, the layers will separate. If the printer pauses, it will most certainly result in a failed print due to layer separation.
Since the printer is in a server room, the temperature is well regulated though if the cause were temperature variations, I'd expect it would affect more filaments.