Hi @marcottt, I was checking your configuration folder. What I see is that running 4.0 with this folder I already get "Configuration Errors", because apparently you have an Anycubic Kossel Plus loaded, but we don't have this printer definition by default in Cura. Probably you got it from another source or you are using another cloned version of Cura that includes this definition.
If I upgrade to Cura 4.1 or Cura 4.2, I don't see any problem except the aforementioned one. So the Version Upgrade works well in my computer. The only way to lose all your configuration is either deleting the folder manually or clicking in this "Reset" button. In case you pressed that button, a backup is stored, so you can always recover from it.
Please let me know if this is the same behaviour that you see.