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Hi every one, I got the same issue as you today. Context: I plugged an additionnal screen while Fusion 360 and Cura were launched. Actions done: I uninstalled the v 4.0 then install the 4.1.. Pb still present. Then I went to the folder were Cura.exe is (C:\Program Files\Ultimaker Cura 4.1), Clic right on Cura.exe and select 'Solve compatibility problems' from the menu. Then I selected the option "try recommanded parameters"... After few seconds Cura 4.1 launched succesfully. Hope this 'repare' will last and hope this will help you also.