I just found some new information that seems to agree with the example I shared. That gives me the confidence to proceed with the CAD work I need to do to prepare my actual model.
I'd still like to hear about any other approaches, caveats, related settings, etc.
If it's helpful, here are the references I found on this topic...
I based my first attempt on this helpful video -
I then played around with Cura to create the example I shared.
I also went looking for related discussions and, at first, I didn't find anything of interest. Since posting this question, I found this valuable discussion with additional details - https://3dprinting.stackexchange.com/questions/6522/different-infill-in-the-same-part . That post actually links back to a discussion here -