I have a Ryzen 1600 and ASUS b350-f Strix MB. Latest version of Cura 4.6.1 still crashes intermittently. Sometimes it will be while using it. Other times if I leave I alone for a while. My hunch is the ASUS motherboard. I have two Ryzen systems in house and I have not noticed the same behaviour on the other one. The one that so far seems ok has a Ryzen 3700 with an aorus MB in it.