I have updated to the latest version of cura (4.7.1 at the time of writing) and am still running into the same issue. I even tried uploading stl files under a different printer (CR10 from the drop down menu selection). Everything about the software works fine until I try and upload any kind of file, about .5 seconds after the program opens file explorer the message cure.exe has stopped working and the program closes.
Also, I am a novice at best so I don't really follow what you were saying in your response maht. The "settings stack" to which you are referring should be isolated to the one printer profile and therefore I shouldn't experience the same problem when using any of the drop down printer profiles in the setup menu, should I?
cura.log