I have two small stl files which CURA complains that they are ' not manifold' on loading for slicing but slices anyway. On printing small holes wanted through the base layer are ignored and printed filled in. (I have checked the CURA setting for mesh and holes) Other holes in other locations printed OK. STL files were produced by TurboCad Pro, am using CURA 4.6 on windows 10 64 bit. One example stl file is attached
Alice handrail knob sliced.STL