I've got a Chinese Ender-3 Pro knock off called a XVico X3S. Turns out that the USB chipset on their motherboard didn't auto load on my windows 10 box. The chipset is a CH340. I had to find and install the driver to get a response from the printer.
Then I found that the printer will only connect at 115,200 (auto detect never found the printer so I had to find this baud rate by trial and error)
With the driver and the correct baud rate, I can connect to the printer just fine.
Now, there's one other issue with communication.... occasionally, a gcode command gets lost and the printer doesn't know how to retry so the print pukes.