Judging from the facets visible in both of your photos. I'd say the resolution of the STL file is far too low. It appears that you are modeling a stretch blown PET bottle? Working for a plastic bottle manufacture, practically all I print are models of bottles. I always print them standing upright with PVA support for the bottom push up detail.
I've encountered some problems with supports using Cura 2.5 so still using Cura 2.4 Ultimaker3 Ext.
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gr5 2,071
It looks like it might not be slicing it correctly. Probably an error in the cad model. Look at it in xray view. If you see anything in the color red that is a problem. If there is no red then try removing "fix horrible A". Somewhere deep in advanced menus.
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