Basically the prime tower helps to reduce oozing and to prime the nozzle before printing the next layer. When printing dual colors it can help to get a sharper and cleaner separation between the two colors. In most cases it is not needed, but if you need a perfect surface in dual color mode, then give it a try.
When printing with support materials, it is not needed in my opinion.
Here is some more info also about the settings:
https://ultimaker.com/en/resources/49701-dual-extrusion
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Framar 38
It useful when you have material that is drooling when the second nozzle starts to heat but if not, you don't need it.
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