Wait - make sure "remove all holes" is unchecked in mesh fixes. In fact make sure all the mesh fixes are default. When I do "remove all holes" I get something similar to what you describe.
Also check the Z value position for your part. Did you lift if up off the table on purpose? I'm guessing yes. It's normally zero but you can lift it up a few mm when printing in your "bowl" orientation to get consistent support. Click on the part, select the MOVE tool on the far left of cura and look at the Z value. Normally it's always zero.
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gr5 2,269
There's nothing wrong with your STL file. It's water tight. Normals look good. And it slices just fine for me in either orientation.
Please attach your project file - it will contain your STL, your machine (printer) settings, filament settings, and all your hundreds of cura settings. Do menu commands "file" "save project" and post that file.
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