[Ultimaker cura 4.2.1]

Has anyone been having problems with the new version of Cura?  Ever since I downloaded it I have not been able to print out of both nozzles for a print.  

[3D printing problems]

Unfortunately I have already tried that idea as well.  Included a pathway of the steps I took to make sure we were talking about the same thing.  After doing this I have still been getting the same error.

[3D printing problems]

I work at a manufacturing plant and we just recently got the Ultimaker s5.  I have a simple problem, however I cannot figure it out.  This picture below is a warning I get when I try to print something.  I already have  PVA Natural loaded into the second printer core, so I'm fairly certain that isn't the problem.  I have also checked through my setup on cura multiple times and have not seen any mistakes.  Anyone know what the problem is?