Howdy SLmona91 - Working with Nylon can be a real pain. The parameters that gr5 suggested will set you on the right path. However, even with the printer perfectly configured, I struggled with this for quite some time until I witnessed first hand what was causing my prints to fail. I noticed a small piece of filament coming directly out of the print head was waving around in the air. Upon further investigation, I realized a very small draft was impacting my print quality (probably from a ceiling fan in my office) based on that finding, I purchased the advanced 3D printing kit and problem solved, the front enclosure kept the printing environment draft free which is critical. That combined with the adhesion paper that came with the kit insured my prints maintained a perfect print quality. I will warn you that if you use the adhesion paper, your print will definitely be stuck to the print bed and you may find it difficult to remove. I would suggest you get the advanced 3D printing kit if you don't already have it and then experiment with and without the adhesion paper. Also, as Taulman suggested in my original post, for larger prints with Nylon, I would never exceed 60% fill although it sounds like that's not the issue with your print. Hope that helps.