Axador

Good day together I'm doing my first steps with 3D printing and calibrating my printer in Cura 5.2.1. Now I have come across the point that I have found the values retraction speed and distance both in the filament setting as well as in the printer setting and do not understand which values dominate in the end, respectively I have to set for the calibration. I do not have to create a separate pressure profile for each filament, right? Which of the values that occur both in the filament as well as in the printer setting I have to calibrate? I hope that I have expressed myself clearly and am curious about your answers.