UltiMaker uses functional, analytical and tracking cookies. Tracking cookies enhance your experience on our website and may also collect your personal data outside of Ultimaker websites. If you agree with the use of tracking cookies, click “I agree, continue browsing”. You can withdraw your consent at any time. If you do not consent with the use of tracking cookies, click “Refuse”. You can find more information about cookies on our Privacy and Cookie Policy page.
Had the same problem. After some investigation (like event log) I figured out that I had to add Cura.exe and CuraEngine.exe to the Windows Defender exceptions... after doing so cura 4.4.1 started up ok.