Slic3r hangs on 32-bit system and causes a heap (memory) error on 64-bit. In both cases it either does not complete or eventually crashes completely. In either case it heavily utilizes CPU >98%.
Last time I tried Slic3r, I had the same issue, people told me that you had to disable the "multithreaded" support, as it was causing crashes. Not sure if that is still the case, as this was half a year ago.
(Funny fact, Cura is still faster, and still single threaded)
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illuminarti 18
In the printer settings -> advanced, try setting the resolution to a non-zero value. I generally use 0.05, assuming my layer height is at least twice that. That helps it to simplify the mesh to make the slicing task more manageable.
Also, you should read http://www.extrudable.me/2013/11/03/slic3r-strange-defaults-causing-qu-bd-woes/, and consider setting all of the extrusion width settings to equal your nozzle width (0.4mm, usually).
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