I use Cura 4.12.1 sorry do not know me so well with it yet
Thanks for the log files. It does not give me the "golden tip" to fix your issue yet. In your screenshot it seems like Cura cannot find a file that should come with Cura. Can you have a look in "C:\Program Files\Ultimaker Cura 4.12.1\resources\qml\Preferences" to see if ProfileTab.qml exists? For me that folder looks like this (for you the icons may be different, but all these files should be there):
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ahoeben 1,987
We need more information. What version of Cura do you use? If you go to Help->Show Configuration folder… there should be a file named cura.log. Please post a link to that file
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