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Cura cannot cope with big file?

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I wish to print a model of the calcaneum (heel bone). I have converted a CT scan and the STL is 80Mb in size. As the calcaneum is a solid bone, I assume that the slicing takes some time. I did get to the point of having the gcode with a 30 hour print once. I want to make some changes to speed up the print - such as scale down the model and increase the print speed but now Cura simply gets stuck when building the gcode.

Is this a known problem with Cura that it cannot cope with big files




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