Just make sure it is lubed and running smoothly... Don't push on if you discover a problem, but fix it before it gets worse/damages the printer...
Machines like this and their components are designed to last a long time doing what they do, but if you run a 20 hour print job with a skewed belt, mis-aligned axis or similar, you will wear down these components much faster...
from what everyone says, this should be no problem for the printer
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