Cura does do this. Although I think they changed the name of this maybe. I think it's this one:
infill layer thickness
It must be an integer of normal layer height. So your example of 0.05 and 0.2 should work. Note that if the part has sloping walls it gets messy. But if your walls are all vertical then it works great.
No thats not possible in Cura, you can only use one layer height for all extruders and all walls.
If you really need that, Simplify3D can do that.
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