It's difficult to compare temps across different printers, but 180 is quite low for PLA; particularly when printing with thick layers - so depending on the throughput capability of your extruder, and the linear speed you are printing at, you might get better results printing at a higher temperature. Certainly the rough finish you're seeing there looks a lot like your smearing PLA paste onto the print, rather than extruding smoothly.
One of the differences of Cura is that it doesn't really provide any kind of interface layers between grid infill layers and the solid top surfaces. As a result, the first few layers on the top of objects tend to go down poorly. But if you give it more layers - I'd say at least 5 - then you can still get a smooth finish on the top.
Regarding the issue with Slic3r - I'm not really sure what is going on there. One thing to be wary of with Slic3r is that you really need to manually set your extrusion widths (=nozzle width) otherwise it can do some odd things that may over load your extruder; the resulting under-extrusion might cause the gaps you're seeing.
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gr5 2,265
1) 180C is quite cold. try 220C.
2) Can you show the other side of the tardis? I'm confused as to what the problem is. But are you printing in mid-air maybe?
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