UlrichC-DE 114
The material station can help with large parts (> 750g) or with sensitive filaments (PA, PVA). Also for serial printing or when the printer is used heavily (>8h) during the day. Also over night when changing material. The station does not accelerate the printing process (rather the opposite). But it can reduce the manual changeover time between filament rolls.
If you have multiple 3D printers or a small production run, you'll appreciate it. Those are more economic considerations. For experimentation, I find the Material Station to be a hindrance. It turns the S5 into an automated black box, so to speak. The Material-Station is not adjustable and depends on preconceived profiles.
With filaments from other manufacturers the compartibility is not absolutely necessary but a similarity to generic profiles should be given. If this is not the case, the printer can, as you have found out, be returned to the normal roll feed. A parallel operation of material station and roll feeder is not possible. A conversion is cumbersome. Plug and Bowden of the material station must be removed. The roll holder must be plugged in.
I would also say that an S5 alone with Airmanager is the better choice in this case. The option material station can be purchased later. The Airmanager is also not adjustable but it creates constant conditions in the working area of the printer.
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fbrc8-erin 298
To print with the Material Station, you really need a profile for that specific material since the profile controls the cleaning process at the end of the print to make sure that the nozzle is clear and ready for whatever your next material is. If it didn't do the cleaning, and you printed ABS and then tried to print PLA, you'd have under extrusion issues; this process in the firmware/material profile takes care of that. Ultimaker is adding more profiles for the Material Station as the filament manufacturers in the Material Alliance make them available.
Other factors related to Material Station compatibility also include the size of the spool and spool core diameter. If the spool physically does not fit well inside the MS, it's not going to unwind well.
If you have a specific material that you have to use that doesn't have a profile supported for the MS, then I'd recommend going with the S5, or the S5 with the Air Manager--the Air Manager is handy, even without the MS. The Material Station has a lot of ways that it's useful, but it sounds like it might not be the right fit for that particular project.
It looks like there is one anti-bacterial filament in the Marketplace with a MS profile: https://marketplace.ultimaker.com/app/cura/materials/Daniel/Copper3D_PLActive_2019
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