Is this with a printerbot?
It really depends alot on your setup.
A good idea is to create a gcode that extrudes a certain amount of material, say 100 mm, and then measure what your machine actually extrudes.
Multiply that by the average diameter of your filament, and you've got the total volume extruded. Divide by the diameter you've set in cura times a hundred and you've got the flow rate you should set, unless I'm mistaken or made a math error.
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Daid 306
I think you might be over-extruding then, which will give different results on different parameters.
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